diff --git a/plat/st/stm32mp1/bl2_plat_setup.c b/plat/st/stm32mp1/bl2_plat_setup.c
index e87c529..7eaf0ed 100644
--- a/plat/st/stm32mp1/bl2_plat_setup.c
+++ b/plat/st/stm32mp1/bl2_plat_setup.c
@@ -490,5 +490,19 @@
 
 void bl2_el3_plat_prepare_exit(void)
 {
+	uint16_t boot_itf = stm32mp_get_boot_itf_selected();
+
+	switch (boot_itf) {
+#if STM32MP_USB_PROGRAMMER
+	case BOOT_API_CTX_BOOT_INTERFACE_SEL_SERIAL_USB:
+		/* Invalidate the downloaded buffer used with io_memmap */
+		inv_dcache_range(DWL_BUFFER_BASE, DWL_BUFFER_SIZE);
+		break;
+#endif
+	default:
+		/* Do nothing in default case */
+		break;
+	}
+
 	stm32mp1_security_setup();
 }